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Quantitative Structure-activity Relationship Study on the Antioxidant Activity of Carotenoids
Carotenoids are a family of effective active oxygen scavengers, which can reduce the danger of occurrence of chronic diseases such as cardiovascular disease, cataract, cancer, and so on. The quantitative structure-activity relationship (QSAR) equation between carotenoids and antioxidant activity was established by quantum chemistry AMI, molecular mechanism (MM+) and stepwise regression analysis methods, and the model was evaluated by leave-one-out approach. The results showed that the significant molecular descriptors related to the antioxidant activity of carotenoids were the energy difference (EHL) between the lowest unoccupied molecular orbital (LUMO) and the highest occupied molecular orbital (HOMO) and ionization energy (Eiso). The model showed a good predictive ability (Q2 >0.5).
作 者:SUN Yu-Jing PANG Jie YE Xing-Qian Lü Yuan LI Jun 作者单位:SUN Yu-Jing,YE Xing-Qian,Lü Yuan,LI Jun(College of Biosystem Engineering and Food Science,Zhefiang University,Hangzhou 310029,China)PANG Jie(College of Food Science,Fujian Agriculture and Forestry University,Fuzhou,Fujian 350002,China)
刊 名:结构化学 ISTIC SCI PKU英文刊名:CHINESE JOURNAL OF STRUCTURAL CHEMISTRY 年,卷(期): 28(2) 分类号:O6 关键词:quantitative structure-activity relationship antioxidant activity carotenoidsGeochemical significance of the relative enrichment of pristane and the negative excursion of δ13CPr across the Permian-
Changes in the distribution of isoprenoid hydrocarbons and in δ13Ckero or δ13CPr across the section from the Changxing Formation to the lower Yinkeng Formation at Meishan (the GSSP of PTB) are studied, in which a relative enrichment of pristane and a sharp shift in both δ13Ckero and δ13Cmole near the boundary are revealed. A possible mechanism for the abnormal accumulation of pristane near PTB is suggested: Lipids in some marine animals and their metabolites, rich in pristane, can be preserved and accumulate in some suitable depositing facies under certain special conditions, such as the catastrophic death of animals and/or developing of an anoxic water column, and thus the pristane enrichment occurs in the sediment. The occurrences of isoprenoid enrichment and high Pr/Ph ratios have been found in other typical marine anoxic sediments accompanied by mass extinction in various extent during the most important geological periods, such as Late Ordovician, end of Devonian, Early Jurassic and Late Cretaceous. These occurrences support to a certain extent the above mechanism that interprets the genesis of a high Pr/Ph ratio in some typical marine anoxic sediments. The synchronous sharp negative shifts in δ13Cmole, δ13Ckero and δ13Ccarb from Beds 24 to 26 of the Meishan profile indicate that a sudden and strong variation of carbon source in the atmosphere-ocean system occurred during the quick but equable evolution from the end-Permian to Early Triassic, and the coupling between the pristane enrichment and negative shift in δ13Ckero and δ13CPr may well indicate the importance of the release of methane hydrates and marine anoxia in the end-Permian mass extinction.
作 者: 作者单位: 刊 名:科学通报(英文版) SCI英文刊名:CHINESE SCIENCE BULLETIN 年,卷(期): 50(19) 分类号:P3 关键词:PTB pristane carbon isotope ratio animal lipids marine anoxia用法总结
1、their在句中只可用作定语,其后常接复数名词。
2、有时their还可用作动名词的逻辑主语。
3、they和them和their的联系:them是they的`宾格,一般在介词后;their是they的形容词性物主代词,后面加名词;they是代词,在句子中一般用作主语。
A mammoth undertaking that involved digging into the side of a cliff face.
一项凿进崖面的巨大任务。
It was the will of a merciful God that all should be saved.
拯救所有的.人是慈悲上帝的意愿。
Part of why we cleave to sports is that excellence is so measurable.
我们坚持体育运动的部分原因是优异成绩很容易测评。
[with obj.]a heatwave so intense that it shrivelled the grapes in every vineyard.
一个强得使所有葡萄园里的葡萄都枯萎的热浪。
Is she going?’ ‘That's just it — she can't make up her mind.
’ “她去吗?”“那正是问题所在——她拿不定主意。
I thought that I would fly a kite for a somewhat unfashionable theory.
我想要为有点不合潮流的理论试探一下舆论。
We are still friends, though, which is good.
不过我们仍然是朋友,这令人感到欣慰。
There have been many changes in recent years.
近几年发生了许多变化。
There are still a few residual problems with the computer program.
电脑程序还有一些残留问题。
No new SARS cases have been reported in the region.
该区没有新增非典型肺炎病例。
A number of measures were taken to alleviate the problem.
采取了一系列措施缓解这个问题。
The two leaders are battling for control of the government.
两位领导人正在争夺政府控制权。
There are qualitative differences between the two products.
这两种产品存在着质的差别。
例句:
1.We emerged into bright sunlight.
我们来到明媚的阳光下。
2.The ship steered into port.
船驶进港口。
3.We walked into the foyer.
我们走进前厅。
4.I sank into an armchair.
我坐到扶手椅上。
5.The boys grew into men.
这些男孩长大成为男人了。
Don't read too much into what she says.
不要在她的.话里加进太多自己的理解。
I've had to put my plans into cold storage.
我不得不把我的计划暂时搁置起来。
Many people think that party politics should not enter into local government.
许多人都认为,地方政府内不应拉帮结派。
He has carried out extensive research into renewable energy sources.
他已经对再生能源进行了广泛研究。
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